Central obesity in the adult populations of the Altai Republic and the Republic of Tuva. Anthropological and genetic aspects

Parfenteva O.I., Pravednikova A.E., Aiyzhy E.V., Popova E.V., Balinova N.V., Zadorozhnaya L.V., Khomyakova I.A., Bondareva E.A.

 

VESTNIK ARHEOLOGII ANTROPOLOGII I ETNOGRAFII   1 (60)  (2023)

https://doi.org/10.20874/2071-0437-2023-60-1-11 

 

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Abstract

In the present study, we identified the factors affected central obesity prevalence in the adult Altains, Russians and Tuvans permanently residing in the Altai and the Tuva Republics. The data was collected in 20182020. The examination program included anthropometrical examination and the genetic testing of females and males, aged 1835 years. Anthropometrical examination was carried out in accordance with the guidelines accepted in the Research Institute and Museum of Anthropology. Body composition was analyzed by bioelectrical impedance analyzer. The SNPs rs1800592 UCP1, rs660339 UCP2 and rs1800849 UCP3 were assessed. The prevalence analyses of underweight, overweight and general obesity in the groups of female and males were conducted. The anthropometric indices were used to estimate the prevalence of central obesity. General obesity occurred more often in the group of Altai people, whereas in the Tuva people the central obesity is more pronounced. The Altai and Tuva people are alike in the total body measurements, whereas Russians were significantly higher. All studied groups demonstrated the sexual dimorphism of the body composition and waist to hip ratio. No significant differences in waist to height ratio between males and females were identified in the studied groups. No association between genetic variants and the obesity-related traits, which reflect the body fat and its distribution, was revealed. All factors included in the model are able to predict 8 % of the variability of the central obesity-related traits. Ethnic background contributes the most to the variability of the central obesity index.

Keywords: biological anthropology, central obesity, WHtR, Tuva, Altai, adults, UCP.

 

Funding. The study was supported by RFBR grants No. 20-49-040004 (for E.V. Popova), No. 18-59-94015 (for E.A. Bondareva and O.I. Parfentyeva) and the planned topic AAAA-A19-119013090163 -2 "Anthropology of Eurasian populations (biological aspects).

 

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.

Accepted: 05.12.2022

Article is published: 15.03.2023

 

Parfenteva O.I., Institute and Museum of Anthropology, Lomonosov Moscow State University Mokhovaya st., 11, Moscow, 125009, Russian Federation, E-mail: parfenteva.olga@gmail.com, https://orcid.org/0000-0001-7895-6887

 

Pravednikova A.E., Institute of Gene Biology RAS, Vavilova st., 34/5, Moscow, 119334, Russian Federation, E-mail: pravednikova.anya@yandex.ru, https://orcid.org/0000-0002-4572-5318

 

Aiyzhy E.V., Tuvan State University, Lenina st., 5, Kyzyl, 667000, Russian Federation, E-mail: aiygy@mail.ru, https://orcid.org/0000-0002-4289-3543

 

Popova E.V., Gorno-Altai State University, Lenkina st., 1, Gorno-Altaisk, 649000, Russian Federation, E-mail: ms.biolog@mail.ru, https://orcid.org/0000-0002-4241-3669

 

Balinova N.V., Research Centre for Medical Genetics, Moskvorechye st., 1, Moscow, 115522, Russian Federation, E-mail: balinovs@mail.ru, https://orcid.org/0000-0001-9493-6544

 

Zadorozhnaya L.V., Institute and Museum of Anthropology, Lomonosov Moscow State University Mokhovaya st., 11, Moscow, 125009, Russian Federation, E-mail: mumla@rambler.ru, https://orcid.org/0000-0002-3143-3226

 

Khomyakova I.A., Institute and Museum of Anthropology, Lomonosov Moscow State University Mokhovaya st., 11, Moscow, 125009, Russian Federation, E-mail: irina-khomyakova@yandex.ru, https://orcid.org/0000-0002-2811-2034

 

Bondareva E.A., Federal Research and Clinical Center of Physical-Chemical Medicine Federal Medical Biological Agency Malaya Pyrogovskaya st., 1a, Moscow, 119435, Russian Federation, E-mail: Bondareva.E@gmail.com, https://orcid.org/0000-0003-3321-7575